Single Use bioprocessing is on the rise as a standard for manufacturing due to the convenience, efficiency and cost savings over traditional stainless steel approaches. In many cases, a limiting factor is the time it takes to move fluid from one area of the process to another. Whether in a single use system or a hybrid stainless steel to single use application where larger connection ports are more common, rapid fluid transfer through larger hose can provide a tremendous time savings for these critical processes. Refine Technology’s CleanLine™ 1.5″ Connector and custom hose assemblies provide simpler sterile set-up and operational efficiency with higher flow rates than traditionally smaller single use connections.
The CleanLine™ Connector provides the benefits of aseptic single use capability while maintaining the reliability typically associated with traditional stainless steel technology.
- Strong, robust 1½ ” connection for high pressure and flow rates
- Single use supports continuous bioprocessing
- Dual seals minimize contamination risk from the inside and outside
- Genderless connecting: less inventory, less complexity, more flexibility
- Connection secured with polysulfone Twist Lock Rivets
- Cleaned, assembled and packaged in an ISO 7 Clean Room
- Gamma and autoclave stable
- More cost effective; less down time
- Hose and custom assemblies available
Applications Include:
- Upstream to downstream transfer
- Media buffer preparation and transfer
- Bioreactor harvest
- Sterile waste removal from process stream
- WFI or sterile water transfers
- Sterile bulk formulation downloads
Anywhere in your process that could benefit from rapid, high volume sterile fluid transfers.
- CleanLine™ Connector body material meets USP Class VI, 21 CFR 177.1655, and is Animal Derived Component Free
- Components are cleaned, assembled, and packaged in an ISO 7 clean room
- Compatible with autoclave and gamma sterilization
- Each lot’s materials of construction have 100% traceability
- Gamma stable up to 50 kGy
- Autoclave stable 124°C for 60 minutes
- Form, fit, and function are maintained following steam and vacuum autoclave cycles
- Vacuum hold up to 26” Hg
- Pressure hold up to 80 psi
- Sterility can be maintained after connection in an uncontrolled environment
- Water flow rate of 290 liters per minute at pressure drop of 0.69 psi
- Press connector halves together until one hears an audible click
- Mate the handles and pull to remove the sanitary shields
- Fasten with polysulfone rivets
| Product | Product Number |
| CleanLine™ 1.5″ Single Use Connector | CLC-1.5 |
| CleanLine™ Single Use Tri-Clamp Connector | CLC-1.5-TC |
| Accessories for use with CleanLine 1.5″ Single Use Connector | |
| Hose Barb to T.C. Adapter | CLCOP:QP-BR |
| 1.5″ x 6″ Fabric Reinforced Silicone Hose | ST:PT-FR-1.5×6 |
| 1.5″ x 12″ Fabric Reinforced Silicone Hose | ST:PT-FR-1.5×12 |
| 1.5″ x 24″ Fabric Reinforced Silicone Hose | ST:PT-FR-1.5×24 |
| 1.5″ x 48″ Fabric Reinforced Silicone Hose | ST:PT-FR-1.5×48 |
| 1.5″ x 6″ Stainless Steel Reinforced Silicone Hose | ST:PT-SS-1.5×6 |
| 1.5″ x 12″ Stainless Steel Reinforced Silicone Hose | ST:PT-SS-1.5×12 |
| 1.5″ x 24″ Stainless Steel Reinforced Silicone Hose | ST:PT-SS-1.5×24 |
| 1.5″ x 48″ Stainless Steel Reinforced Silicone Hose | ST:PT-SS-1.5×48 |
Gamma sterilized connectors and hose, custom lengths of hose, and connector and hose assemblies available upon request.